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Efficient enzyme-catalyzed production of diosgenin: inspired by the biotransformation mechanisms of steroid saponins in <i>Talaromyces stollii</i> CLY-6

Leiyu Cheng, Han Zhang, Haiyang Cui, Mehdi D. Davari, Bin Wei, Wenya Wang, Qipeng Yuan

2021Green Chemistry39 citationsDOI

Abstract

Two novel glycosidases (Rhase-TS and Gluase-TS) were discovered from Talaromyces stollii CLY-6, followed by a whole-enzyme-catalyzed approach for highly efficient diosgenin production from steroid saponins.

Topics & Concepts

DiosgeninBiotransformationSteroidChemistryEnzymeCatalysisGlycosideSaponinOrganic chemistryBiochemistryMedicineHormonePathologyAlternative medicineSteroid Chemistry and BiochemistryPhytochemical Studies and BioactivitiesMicrobial Natural Products and Biosynthesis
Efficient enzyme-catalyzed production of diosgenin: inspired by the biotransformation mechanisms of steroid saponins in <i>Talaromyces stollii</i> CLY-6 | Litcius