Histamine Sensitivity: An Uncommon Recognized Cause of Living Laryngopharyngeal Reflux Symptoms and Signs—A Case Report
Ghiath Alnouri, Nicholas Cha, Robert T. Sataloff
Abstract
A 45-year-old female who had undergone Nissen fundoplication for long-standing laryngopharyngeal reflux (LPR) developed episodes of coughing and throat clearing. Strobovideolaryngoscopy demonstrated evidence of LPR with a reflux finding score of 11. A cough workup including a chest X-ray and pulmonology consultation was negative. Consultation with a nutritionist revealed Histamine intolerance. Histamine-free diet resulted in marked improvement in patient's symptoms and examination.
Topics & Concepts
Laryngopharyngeal refluxMedicineHistaminePulmonologyInternal medicineRefluxThroatGastroenterologyDermatologySurgeryDiseaseFood Allergy and Anaphylaxis ResearchChild Nutrition and Feeding IssuesMast cells and histamine