Optimized Box–Behnken experimental design based response surface methodology and Youden’s robustness test to develop and validate methods to determine nateglinide using kinetic spectrophotometry
Sk Manirul Haque
Topics & Concepts
NateglinideBox–Behnken designResponse surface methodologyDetection limitAbsorbanceChromatographyFactorial experimentRobustness (evolution)ChemistryFractional factorial designDimethyl sulfoxideLinearityAnalytical Chemistry (journal)MathematicsStatisticsType 2 diabetesBiochemistryDiabetes mellitusEndocrinologyOrganic chemistryMedicinePhysicsGeneQuantum mechanicsAnalytical Methods in PharmaceuticalsAntibiotics Pharmacokinetics and EfficacyAnalytical Chemistry and Chromatography