Erythroferrone in iron regulation and beyond
Jodie L. Babitt
Abstract
levels.Knockdown of FIP1L1 in AML cell lines without t(8;21) leads to attenuation of mTORC1 signaling and reduced levels of MYC protein, ultimately promoting differentiation and pointing to a broader role of FIP1L1 in regulating APA in AML.
Topics & Concepts
MedicineInternal medicineIron Metabolism and DisordersTrace Elements in HealthHemoglobinopathies and Related Disorders