Litcius/Paper detail

Peptide Dendrimer-Based Antibacterial Agents: Synthesis and Applications

Suchita Paul, Sandeep Verma, Yu‐Chie Chen

2024ACS Infectious Diseases38 citationsDOIOpen Access PDF

Abstract

stability and multivalence allow them to effectively target multi-drug-resistant strains and prevent biofilm formation. Thus, it is interesting to have an overview of the development and applications of peptide dendrimers in antibacterial research, including the possibility of employing machine learning approaches for the design of AMPs and dendrimers. This review summarizes the synthesis and applications of peptide dendrimers as antibacterial agents. The challenges and perspectives of using peptide dendrimers as the antibacterial agents are also discussed.

Topics & Concepts

DendrimerCombinatorial chemistryAntibacterial peptidePeptideNanotechnologyPeptide synthesisChemistryComputer scienceAntibacterial activityComputational biologyBacteriaBiochemistryBiologyMaterials scienceGeneticsAntimicrobial Peptides and ActivitiesChemical Synthesis and AnalysisDendrimers and Hyperbranched Polymers