Borane-catalysed S–H insertion reaction of thiophenols and thiols with α-aryl-α-diazoesters
Kexin Dong, Xun-Shen Liu, Xiaoyan Wei, Yuting Zhao, Lu Liu
Abstract
Herein, we have developed a novel B(C6F5)3-catalysed S–H bond insertion of thiophenols and thiols with α-aryl-α-diazoesters under mild conditions, furnishing various sulfides in moderate to excellent yield. This method features simple operation, mild conditions, broad substrate scope and easy scale-up, which provide an alternative approach for transition-metal catalysed reaction.
Topics & Concepts
BoraneInsertion reactionArylChemistryYield (engineering)Combinatorial chemistrySubstrate (aquarium)Reaction conditionsScope (computer science)Medicinal chemistryOrganic chemistryCatalysisMaterials scienceComputer scienceGeologyAlkylMetallurgyOceanographyProgramming languageCyclopropane Reaction MechanismsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods