Lactoferrin-tethered betulinic acid nanoparticles promote rapid delivery and cell death in triple negative breast and laryngeal cancer cells
Asim Halder, Megha Jethwa, Pritha Mukherjee, Subarna Ghosh, Suvadra Das, A. B. M. Helal Uddin, Arup Mukherjee, Urmi Chatterji, Partha Roy
Abstract
/M phases of the cell cycle, confirming reduced cell proliferation and significant cell death. Speedy intracellular entry of Lf-BAnp occurred within 30 min. Lf-BAnp design was explored for the first time as safer chemotherapeutic arsenals against complex TNBC conditions.
Topics & Concepts
Triple-negative breast cancerBetulinic acidCytotoxicityCytotoxic T cellCancer researchApoptosisCancer cellBreast cancerCancerPopulationCell growthChemistryMedicineImmunologyPharmacologyBiologyInternal medicineIn vitroBiochemistryGeneticsEnvironmental healthInfant Nutrition and HealthPediatric Hepatobiliary Diseases and TreatmentsATP Synthase and ATPases Research