Mechanistic Approach for Protective Effect of ARA290, a Specific Ligand for the Erythropoietin/CD131 Heteroreceptor, against Cisplatin-Induced Nephrotoxicity, the Involvement of Apoptosis and Inflammation Pathways
Nasrin Ghassemi-Barghi, Zeynab Ehsanfar, Omid Mohammadrezakhani, Sorour Ashari, Shamim Ghiabi, Zahra Bayrami
Topics & Concepts
CisplatinOxidative stressApoptosisChemistryPharmacologyInflammationTumor necrosis factor alphaComet assayProinflammatory cytokineDNA damageCancer researchMolecular biologyImmunologyBiologyBiochemistryInternal medicineMedicineDNAChemotherapyChemotherapy-induced organ toxicity mitigationNanoparticle-Based Drug DeliveryCancer-related cognitive impairment studies