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The thymus regulates skeletal muscle regeneration by directly promoting satellite cell expansion

Yanyan Zheng, Ye Wang, Xin Chen, Lisha Wei, Han Wang, Tao Tao, Yuwei Zhou, Zhihui Jiang, Tiantian Qiu, Zhiyuan Sun, Jie Sun, Pei Wang, Wei Zhao, Ye-Qiong Li, Huaqun Chen, Min‐Sheng Zhu, Xuena Zhang

2021Journal of Biological Chemistry15 citationsDOIOpen Access PDF

Abstract

), which were efficiently incorporated into the regenerative myofibers. We thus propose that the thymus plays an essential role in muscle regeneration by directly promoting satellite cell expansion and may function profoundly in the muscle aging process.

Topics & Concepts

MyogeninMyoDRegeneration (biology)Skeletal muscleCell biologyBiologyMyogenesisSatelliteMyogenic regulatory factorsMyocyteImmunologyEndocrinologyAerospace engineeringEngineeringMuscle Physiology and DisordersGenetics, Aging, and Longevity in Model OrganismsExercise and Physiological Responses