Synthetic approaches to unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles and their MAO-B inhibitory activity. A review
Valentin Karabelyov, Magdalena Kondeva-Burdina, Violina T. Angelova
Topics & Concepts
ChemistryOxadiazoleMonoamine oxidaseLead compoundCombinatorial chemistryMonoamine oxidase BStructure–activity relationshipDrugStereochemistryPharmacologyIn vitroBiochemistryEnzymeOrganic chemistryMedicineClick Chemistry and ApplicationsCholinesterase and Neurodegenerative DiseasesSynthesis and biological activity