Bibenzyl analogue DS-1 inhibits MDM2-mediated p53 degradation and sensitizes apoptosis in lung cancer cells
Hardyanti Eka Putri, Bodee Nutho, Thanyada Rungrotmongkol, Boonchoo Sritularak, Chanida Vinayanuwattikun, Pithi Chanvorachote
Topics & Concepts
ApoptosisMdm2CisplatinCancer researchAnnexinMTT assayCancer cellLung cancerBiologyMolecular biologyCancerChemistryMedicinePathologyBiochemistryChemotherapyGeneticsCancer-related Molecular PathwaysNatural Compound Pharmacology StudiesHedgehog Signaling Pathway Studies