Exploring the effectiveness of the TSR-based protein 3-D structural comparison method for protein clustering, and structural motif identification and discovery of protein kinases, hydrolases, and SARS-CoV-2’s protein via the application of amino acid grouping
Titli Sarkar, Vijay V. Raghavan, Feng Chen, Andrew C. Riley, Sophia Zhou, Wu Xu
Topics & Concepts
Amino acidComputational biologyStructural motifStructural similarityStructural Classification of Proteins databaseCluster analysisBiologyProtein structureStructural bioinformaticsIdentification (biology)Structural alignmentDrug discoveryBiochemistryPeptide sequenceSequence alignmentComputer scienceArtificial intelligenceGeneBotanyMachine Learning in BioinformaticsComputational Drug Discovery MethodsProtein Structure and Dynamics