F-box protein FBXO31 modulates apoptosis and epithelial-mesenchymal transition of cervical cancer via inactivation of the PI3K/AKT-mediated MDM2/p53 axis
Keying Liu, Biyun Xue, Guiqin Bai, Wentao Zhang
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayMdm2ApoptosisChemistryCancer researchCellWestern blotViability assayMolecular biologyCell biologyBiologyGeneBiochemistryCancer-related Molecular PathwaysUbiquitin and proteasome pathwaysAutophagy in Disease and Therapy