Fluoxetine and sertraline based multitarget inhibitors of cholinesterases and monoamine oxidase-A/B for the treatment of Alzheimer's disease: Synthesis, pharmacology and molecular modeling studies
Muhammad Shahid Nadeem, Jalaluddin Azam Khan, Umer Rashid
Topics & Concepts
ButyrylcholinesteraseAcetylcholinesterasePharmacologyMonoamine oxidaseChemistryMonoamine oxidase BMonoamine neurotransmitterMonoamine oxidase ACholinesteraseEnzymeIn vivoAchéSelegilineSertralineBiochemistryAntidepressantMedicineBiologySerotoninInternal medicineDiseaseParkinson's diseaseReceptorHippocampusBiotechnologyCholinesterase and Neurodegenerative DiseasesMedicinal Plants and NeuroprotectionComputational Drug Discovery Methods