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Photoaffinity labeling and bioorthogonal ligation: Two critical tools for designing “Fish Hooks” to scout for target proteins

Endri Karaj, Shaimaa H. Sindi, L. M. Viranga Tillekeratne

2022Bioorganic & Medicinal Chemistry28 citationsDOI

Topics & Concepts

Bioorthogonal chemistryChemistryLinkerIdentification (biology)Computational biologyDrug discoverySmall moleculeCombinatorial chemistryPhotoaffinity labelingClick chemistryBiochemistryBinding siteComputer scienceProgramming languageBiologyBotanyClick Chemistry and ApplicationsChemical Synthesis and AnalysisMonoclonal and Polyclonal Antibodies Research
Photoaffinity labeling and bioorthogonal ligation: Two critical tools for designing “Fish Hooks” to scout for target proteins | Litcius