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Resistance to MET inhibition in MET-dependent NSCLC and therapeutic activity after switching from type I to type II MET inhibitors

Richard Riedel, Jana Fassunke, Hannah L. Tumbrink, Andreas H. Scheel, Carina Heydt, Lena Hieggelke, Matthias Scheffler, Alena Heimsoeth, Lucia Nogová, Sebastian Michels, Jan-Phillip Weber, Rieke Fischer, Anna Eisert, Theresa Westphal, Diana Schaufler, Janna Siemanowski, Michaela A. Ihle, Svenja Wagener‐Ryczek, Roberta Castiglione, Roberto Pappesch, Jan Rehker, Jessica Jürgens, Erich Stoelben, Anne Bunck, Carsten Kobe, Sabine Merkelbach‐Bruse, Martin L. Sos, Reinhard Büttner, Jürgen Wolf

2022European Journal of Cancer29 citationsDOI

Topics & Concepts

KRASMedicineCancer researchTyrosine kinaseAcquired resistanceResistance mutationInternal medicineTargeted therapyKinaseMutationOncologyCancerBiologyColorectal cancerReceptorGenePolymerase chain reactionGeneticsReverse transcriptaseLung Cancer Treatments and MutationsLiver physiology and pathologyMelanoma and MAPK Pathways
Resistance to MET inhibition in MET-dependent NSCLC and therapeutic activity after switching from type I to type II MET inhibitors | Litcius