circRNA_100859 functions as an oncogene in colon cancer by sponging the miR-217-HIF-1α pathway
Peng Zhou, Wei Xie, Hualin Huang, Rongqi Huang, Chao Tian, Hongbo Zhu, Yinghuan Dai, Zhiyuan Li
Abstract
<0.05). Therefore, it was concluded that circRNA_100859 functions as an oncogene in colon cancer by sponging the miR-217-HIF-1α pathway. In addition, the circRNA_100859-miR-217-HIF-1α axis may serve as a novel diagnostic and prognostic biomarker for patients with colon cancer.
Topics & Concepts
OncogeneCancer researchColorectal cancermicroRNACancerMedicineInternal medicineOncologyBiologyCell cycleGeneGeneticsCircular RNAs in diseasesMicroRNA in disease regulationCancer-related molecular mechanisms research