Mitochondrial DNA oxidation propagates autoimmunity by enabling plasmacytoid dendritic cells to induce TFH differentiation
Hongxu Xian, Kosuke Watari, Masafumi Ohira, Jonathan S. Brito, Peng He, Janset Onyuru, Elina I. Zúñiga, Hal M. Hoffman, Michael Karin
Topics & Concepts
Mitochondrial DNAAutoantibodyInflammasomeBiologyImmunologyAutoimmunityCell biologyGeneticsAntibodyInflammationGeneInflammasome and immune disordersinterferon and immune responsesImmune Response and Inflammation