Graphene-extracted membrane lipids facilitate the activation of integrin α<sub>v</sub>β<sub>8</sub>
Serena H. Chen, Jose Manuel Perez‐Aguilar, Ruhong Zhou
Abstract
subunit at this hydrophobic cluster further reveals the importance of a stable T-shaped structure in retaining integrin in its inactive state. Our results agree with previous studies on the interactions between other integrin subtypes and their endogenous activators, suggesting an intriguing role that the graphene nanosheet may play in the integrin-related signal transduction during its interaction with the membrane.
Topics & Concepts
GrapheneProtein subunitIntegrinDomain (mathematical analysis)Materials scienceNanotechnologyChemistryBiochemistryCellGeneMathematicsMathematical analysisCell Adhesion Molecules ResearchPhagocytosis and Immune RegulationGraphene and Nanomaterials Applications