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Brain-targeted Tet-1 peptide-PLGA nanoparticles for berberine delivery against STZ-induced Alzheimer’s disease in a rat model: Alleviation of hippocampal synaptic dysfunction, Tau pathology, and amyloidogenesis

Samar R. Saleh, Aml Abd-Elmegied, Somaya Aly Madhy, Sherine N. Khattab, Eman Sheta, Fatma Y. Elnozahy, Radwa A. Mehanna, Doaa A. Ghareeb, Nihad Abdel-Monem

2024International Journal of Pharmaceutics40 citationsDOI

Topics & Concepts

PLGAMorris water navigation taskChemistryPharmacologyNeuroinflammationNeuroprotectionAlzheimer's diseaseHippocampal formationEndocrinologyInternal medicineMedicineBiochemistryInflammationDiseaseIn vitroAlzheimer's disease research and treatmentsBerberine and alkaloids researchCholinesterase and Neurodegenerative Diseases
Brain-targeted Tet-1 peptide-PLGA nanoparticles for berberine delivery against STZ-induced Alzheimer’s disease in a rat model: Alleviation of hippocampal synaptic dysfunction, Tau pathology, and amyloidogenesis | Litcius