Novel 5-Fluorouracil analogues versus perfluorophenyl ureas as potent anti-breast cancer agents: Design, robust synthesis, in vitro, molecular docking, pharmacokinetics ADMET analysis and dynamic simulations
Farid M. Sroor, Ahmed F. El‐Sayed, Khaled Mahmoud
Topics & Concepts
ChemistryIn vitroDocking (animal)PharmacokineticsCombinatorial chemistryMolecular dynamicsFluorouracilPharmacologyStereochemistryComputational chemistryBiochemistryCancerInternal medicineNursingMedicineCancer Treatment and PharmacologyEstrogen and related hormone effectsCancer therapeutics and mechanisms