Adenine Radical Cation Formation by a Ligand-Centered Excited State of an Intercalated Chromium Polypyridyl Complex Leads to Enhanced DNA Photo-oxidation
Frederico A. Baptista, Dorottya Krizsan, Mark Stitch, Igor V. Sazanovich, Ian P. Clark, Michael Towrie, Conor Long, Lara Martínez‐Fernández, Roberto Improta, Noel A. P. Kane‐Maguire, John M. Kelly, Susan J. Quinn
Abstract
, which locates the dppz in contact with the target purines, is dominated by the LC centered excited state. This work has implications for future phototherapeutics and photocatalysis.
Topics & Concepts
ChemistryGuaninePhotochemistryExcited statePhenazineNucleobaseBase pairMetalLigand (biochemistry)RedoxIntercalation (chemistry)LuminescenceOxidation stateRadical ionDNANucleotideInorganic chemistryOrganic chemistryReceptorOptoelectronicsNuclear physicsPhysicsBiochemistryIonGeneMetal complexes synthesis and propertiesDNA and Nucleic Acid ChemistryClick Chemistry and Applications