Litcius/Paper detail

Advances and developments in transition metal-free benzylic C(sp<sup>3</sup>)–H activation/functionalization reactions

Fatemeh Doraghi, Shahab Kermaninia, Elika Salehi Ghalehsefid, Bagher Larijani, Mohammad Mahdavi

2025RSC Advances7 citationsDOIOpen Access PDF

Abstract

)-H activation/functionalization bond formation can be carried out in the presence of organic/inorganic peroxides, bases, acids, and other radical initiators. These radical transformations also occur under photochemical and electrochemical conditions. In this review, we highlight the C-H activation/annulation or C-H activation/functionalization reactions of benzylic carbon atoms in the presence of non-metal catalysts or promoters or without any catalyst.

Topics & Concepts

Surface modificationAnnulationTransition metalChemistryCatalysisMetalStereochemistryPhotochemistryOrganic chemistryPhysical chemistryCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsRadical Photochemical Reactions