Mercaptoacetamide: A promising zinc-binding group for the discovery of selective histone deacetylase 6 inhibitors
Maurício T. Tavares, Alan P. Kozikowski, Sida Shen
Topics & Concepts
HDAC6ChemistryHydroxamic acidHistone deacetylaseAcetylationDrug discoveryHsp90Heat shock proteinPharmacologyBiochemistryEpigeneticsHistoneStereochemistryBiologyGeneHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and AnalysisProtein Degradation and Inhibitors