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An ultrasensitive electrochemical sensing platform for the detection of cTnI based on aptamer recognition and signal amplification assisted by TdT

Mingjian Lang, Dan Luo, Guangyi Yang, Quanxi Mei, Guangjun Feng, Yang Yang, Zhaohui Liu, Qinhua Chen, Lun Wu

2020RSC Advances47 citationsDOIOpen Access PDF

Abstract

We have developed an ultrasensitive and highly specific electrochemical sensing platform for the detection of cardiac troponin I (cTnI), a recognized biomarker for the diagnosis of acute myocardial infarction (AMI) and related cardiovascular diseases (CVDs).

Topics & Concepts

AptamerSIGNAL (programming language)ElectrochemistryChemistryNanotechnologyComputer scienceMaterials scienceMolecular biologyBiologyElectrodePhysical chemistryProgramming languageAdvanced biosensing and bioanalysis techniquesElectrochemical Analysis and Applications
An ultrasensitive electrochemical sensing platform for the detection of cTnI based on aptamer recognition and signal amplification assisted by TdT | Litcius