Litcius/Paper detail

Regioselective and late-stage polyfluoroarylation of arenes with diverse fluoroaryl nucleophiles <i>via</i> Pd-catalysis

Lei Liang, Yuehui Wang, Chen Li, Hua‐Jie Wang, Qi‐Liang Yang, Chang-Gong Li, Gui-Rong Qu, Hai‐Ming Guo, Hong‐Ying Niu

2022Organic Chemistry Frontiers10 citationsDOI

Abstract

Dehydrogenative coupling of arenes with fluoroaryl nucleophiles enables the efficient synthesis of fluoroaromatic compounds from readily available starting materials.

Topics & Concepts

NucleophileChemistryRegioselectivityCatalysisCombinatorial chemistryCoupling (piping)Organic chemistryMedicinal chemistryEngineeringMechanical engineeringFluorine in Organic ChemistryCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions