Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control
Ian C. Miller, Ali Zamat, Lee-Kai Sun, Hathaichanok Phuengkham, Adrian M. Harris, Lena Gamboa, Jason Yang, John P. Murad, Saul J. Priceman, Gabriel A. Kwong
Topics & Concepts
Chimeric antigen receptorNKG2DTransgeneAdoptive cell transferPhotothermal therapyCell biologyCancer researchCytotoxicityIn vitroAntigenChemistryMolecular biologyT cellCytotoxic T cellBiologyImmunologyMaterials scienceImmune systemBiochemistryNanotechnologyGeneCAR-T cell therapy researchNanowire Synthesis and ApplicationsImmunotherapy and Immune Responses