Supramolecular design based activatable magnetic resonance imaging
Wen‐Chao Geng, Zhe Zheng, Dong‐Sheng Guo
Abstract
Abstract Magnetic resonance imaging (MRI) has been widely used in clinical diagnosis. In recent years, activatable MRI probes responding to specific changes in their microenvironment have been developed. The signal of the MRI probe can be modulated based on supramolecular design, which can include properties such as self‐assembly and molecular recognition. In this review, we summarize the activatable MRI probes based on the design principles of supramolecular chemistry. We also discuss the current challenges and the future perspectives for how activatable MRI can achieve more extensive clinical applications for cancer therapy.
Topics & Concepts
Magnetic resonance imagingSupramolecular chemistryNanotechnologyMaterials scienceNuclear magnetic resonanceMedicineChemistryRadiologyPhysicsMoleculeOrganic chemistrySupramolecular Chemistry and ComplexesSupramolecular Self-Assembly in MaterialsMolecular Sensors and Ion Detection