A copper missile-triggered power coalescence and death vortex within tumor cell mitochondria for synergistic cuproptosis/phototherapy/chemotherapy
Yicheng Jiang, Shuhan He, Xiang Niu, Linghui Duan, Yuxiang Lin, Wenyu Huang, Zhenghong Wu, Xiaole Qi
Abstract
The CCTH nanoparticles trigger power coalescence and death vortex within tumor cell mitochondria, producing potent anti-tumor efficacy through cuproptosis/phototherapy/chemotherapy synergistic therapy.
Topics & Concepts
Coalescence (physics)MitochondrionChemotherapyVortexCopperProgrammed cell deathCellApoptosisTumor cellsApoptotic cell deathCancer researchNanotechnologyChemistryCell biologyMaterials scienceMedicineBiologyPhysicsInternal medicineMetallurgyBiochemistryMechanicsAstrobiologyNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisAutophagy in Disease and Therapy