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A novel multifunctional SERS microfluidic sensor based on ZnO/Ag nanoflower arrays for label-free ultrasensitive detection of bacteria

Yue Liu, Guanwen Su, Wei Wang, Hongyuan Wei, Leping Dang

2024Analytical Methods14 citationsDOI

Abstract

. Additionally, the antibacterial properties of ZnO/Ag heterojunction nanostructures are studied, suggesting their ability to inactivate bacteria. Compared with the traditional Au-enhanced chip, the sensor preparation is easy, safe, reliable, and low-cost. Moreover, the ZnO nano-array exhibits a large specific surface area, high interception ability, stronger and uniform SERS performance, and effective and reliable detection of trace pathogens. This work provides potential future ZnO/Ag microfluidic SERS sensor applications for rapid, unlabeled, and trace pathogens detection in clinical and environmental applications, potentially achieving breakthroughs in early detection, prevention, and treatment.

Topics & Concepts

NanoflowerMicrofluidicsNanotechnologyMaterials scienceBiosensorChemistryNanostructureBiosensors and Analytical DetectionGold and Silver Nanoparticles Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniques
A novel multifunctional SERS microfluidic sensor based on ZnO/Ag nanoflower arrays for label-free ultrasensitive detection of bacteria | Litcius