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Recurrent Uterine Smooth-Muscle Tumors of Uncertain Malignant Potential (STUMP): State of The Art

Alessandro Rizzo, Angela Dalia Ricci, Maristella Saponara, Antonio De Leo, Anna Myriam Perrone, Pierandrea De Iaco, Maria A. Pantaleo, Margherita Nannini

2020Anticancer Research40 citationsDOIOpen Access PDF

Abstract

The term 'uterine STUMP' (smooth-muscle tumors of uncertain malignant potential) is currently used to define a heterogeneous group of uterine tumors distinct from leiomyomas and leiomyosarcomas. This rare entity is often characterized by a slow growth and protracted patient survival when compared to leiomyosarcomas but few data are available about its clinical management and outcome. In this review, we summarize the current state of knowledge about uterine STUMP, with a particular focus on cases of recurrence.

Topics & Concepts

Smooth muscleSmooth Muscle TumorMedicineLeiomyomaUterusLeiomyosarcomaUterine leiomyomaIn uteroPathologyGynecologyInternal medicineBiologyPregnancyGeneticsFetusUterine Myomas and Treatments
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