Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast <i>in vivo</i> bioimaging
Liao Zhang, Chenxu Yan, Yutao Zhang, Dun Ma, Jialiang Huang, Zijun Zhao, Yining Tao, Caiqi Liu, Juan Li, Weihong Zhu, Zhiqian Guo
Abstract
We design a novel “crossbreeding” NIR-II dye, which can serve as a platform for activatable NIR-II probes with small spectral crosstalk, thereby succeeding in imaging H 2 O 2 in an APAP-induced liver injury model with high signal-to-background ratio.
Topics & Concepts
BODIPYIn vivoCrosstalkContrast (vision)Near-infrared spectroscopyChemistryMaterials scienceFluorescenceNanotechnologyOpticsPhysicsBiologyBiotechnologyNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsAdvanced Nanomaterials in Catalysis