Ginsenoside Rk1 alleviates LPS-induced depression-like behavior in mice by promoting BDNF and suppressing the neuroinflammatory response
Zhiman Li, Lijuan Zhao, Jianbo Chen, Chang Liu, Shanshan Li, Hua Mei, Di Qu, Zijun Shao, Yinshi Sun
Topics & Concepts
Tail suspension testPharmacologyNeuroprotectionTropomyosin receptor kinase BBehavioural despair testLipopolysaccharideLipid peroxidationChemistryWestern blotMalondialdehydeNeuroinflammationNeurotrophic factorsInflammationTumor necrosis factor alphaOxidative stressMedicineEndocrinologyInternal medicineHippocampusBiochemistryReceptorAntidepressantGeneTryptophan and brain disordersGinseng Biological Effects and ApplicationsNeuroinflammation and Neurodegeneration Mechanisms