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Exploration of the Use of Natural Compounds in Combination with Chemotherapy Drugs for Tumor Treatment

Jianping Wu, Yunheng Li, Qiaojun He, Xiaochun Yang

2023Molecules70 citationsDOIOpen Access PDF

Abstract

Currently, chemotherapy is the main treatment for tumors, but there are still problems such as unsatisfactory chemotherapy results, susceptibility to drug resistance, and serious adverse effects. Natural compounds have numerous pharmacological activities which are important sources of drug discovery for tumor treatment. The combination of chemotherapeutic drugs and natural compounds is gradually becoming an important strategy and development direction for tumor treatment. In this paper, we described the role of natural compounds in combination with chemotherapeutic drugs in synergizing, reducing drug resistance, mitigating adverse effects and related mechanisms, and providing new insights for future oncology research.

Topics & Concepts

ChemotherapyDrugMedicineDrug resistanceAdverse effectChemotherapeutic drugsPharmacologyNatural (archaeology)Intensive care medicineOncologyInternal medicineBiologyMicrobiologyPaleontologyCancer Mechanisms and TherapyCancer-related Molecular PathwaysHistone Deacetylase Inhibitors Research
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