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LC-HRMS and NMR studies for the characterization of degradation impurities of ubrogepant along with the in silico approaches for the prediction of degradation and toxicity

Sowmya Chaganti, Usha Chauhan, Nehal Bhatt, Hemasree Kommalapati, Vijaya Madhyanapu Golla, Pushpa Pilli, Gananadhamu Samanthula

2024Journal of Pharmaceutical and Biomedical Analysis18 citationsDOI

Topics & Concepts

ChemistryForced degradationHydrolysisDegradation (telecommunications)Hydrolytic degradationChromatographyAmmonium formateNuclear magnetic resonance spectroscopyHigh-performance liquid chromatographyOrganic chemistryComputer scienceTelecommunicationsMigraine and Headache StudiesCholinesterase and Neurodegenerative DiseasesAnalytical Methods in Pharmaceuticals
LC-HRMS and NMR studies for the characterization of degradation impurities of ubrogepant along with the in silico approaches for the prediction of degradation and toxicity | Litcius