Ligand-controlled regioselective cascade C–C/C–F cleavage/annulation of <i>gem</i>-DFCPs: a divergent synthesis of pyrroles
Tian-Shu Wu, Yong-Jiu Hao, Zhong‐Jian Cai, Shun‐Jun Ji
Abstract
This work describes a ligand-controlled regioselective ring-opening/defluorinative annulation of gem -DFCPs with enaminones, which provides an alternative strategy for the divergent synthesis of pyrroles.
Topics & Concepts
AnnulationRegioselectivityChemistryLigand (biochemistry)Ring (chemistry)Cleavage (geology)StereochemistryCascadeDivergent synthesisCombinatorial chemistryOrganic chemistryCatalysisReceptorFracture (geology)BiochemistryChromatographyEngineeringGeotechnical engineeringFluorine in Organic ChemistrySynthesis and Characterization of PyrrolesCyclopropane Reaction Mechanisms