Thio(seleno)cyano-difluoroalkylation of Alkenes Using Visible-Light Photocatalysis
Ye Rin Choi, Seok Beom Lee, Jae Kyun Lee, Yoonna Kwak, Hongchan An, Sungwook Choi, Ki Bum Hong
Abstract
A mild and efficient three-component thio(seleno)cyano-difluoroalkylation of simple alkenes is demonstrated using an iridium(ruthenium) photocatalyst. This protocol provides a direct and regioselective installation of both C–S(Se)CN [thio(seleno)cyanation] and C–C F (difluoroalkylation) bonds.
Topics & Concepts
ChemistryThio-RegioselectivityPhotocatalysisCyanationRutheniumIridiumCombinatorial chemistryPhotochemistryOrganic chemistryCatalysisFluorine in Organic ChemistrySulfur-Based Synthesis Techniques