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Digital Light Processing of Thermoresponsive Hydrogels from Polyproline‐Based Star Polypeptides

Robert D. Murphy, Muireann Cosgrave, Nicola Judge, Ernesto Tinajero‐Díaz, Giuseppe Portale, Bing Wu, Andreas Heise

2024Small13 citationsDOIOpen Access PDF

Abstract

The first report of star poly(L-proline) crosslinkers is disclosed for digital light processing 3D printing of thermoresponsive hydrogels. Through chain end functionalization of star poly(L-proline)s with methacryloyl groups, access to high-resolution defined 3D hydrogel structures via digital light processing is achieved through photoinitiated free radical polymerization. Changing the poly(L-proline) molecular weight has a direct influence on both thermoresponsiveness and printability, while shape-morphing behavior can be induced thermally.

Topics & Concepts

Self-healing hydrogelsPolyproline helixMaterials scienceMorphingPolymer chemistryStar (game theory)PolymerizationChemical engineeringPolymerChemistryComposite materialComputer sciencePeptideComputer visionBiochemistryEngineeringMathematical analysisMathematicsAdvanced Materials and MechanicsSilk-based biomaterials and applicationsAdvanced Sensor and Energy Harvesting Materials