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Spectrum of Antibiotic Activity and Its Relevance to the Microbiome

Ayman Grada, Christopher G. Bunick

2021JAMA Network Open13 citationsDOIOpen Access PDF

Abstract

dosing, duration of use, and route of administration. Additionally, it will be important to investigate differences in outcomes related to specific classes of antibiotics, as well as whether monotherapy or polytherapy of antibiotics was used. It may be worthwhile to investigate how the interleukin-4 and interleukin-13 pathways, which are implicated in AD, are altered by antibiotic usage. It is important to avoid painting narrow-spectrum and broad-spectrum antibiotics with the same brush because narrow-spectrum and targeted antibiotics are among the main ways physicians will practice antibiotic stewardship in the future.

Topics & Concepts

MicrobiomeRelevance (law)AntibioticsMedicineLibrary scienceSociologyMicrobiologyBiologyPolitical scienceGeneticsComputer scienceLawGut microbiota and healthClostridium difficile and Clostridium perfringens researchBacterial Identification and Susceptibility Testing
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