Litcius/Paper detail

Targeting PD-L2–RGMb overcomes microbiome-related immunotherapy resistance

Joon Seok Park, Francesca S. Gazzaniga, Meng–Huang Wu, Amalia K. Luthens, Jacob E. Gillis, Wenfeng Zheng, Martin W. LaFleur, Sarah B. Johnson, Golnaz Morad, Elizabeth M. Park, Yifan Zhou, Stephanie S. Watowich, Jennifer A. Wargo, Gordon J. Freeman, Dennis L. Kasper, Arlene H. Sharpe

2023Nature183 citationsDOIOpen Access PDF

Topics & Concepts

BlockadeMicrobiomeImmune checkpointImmunityImmune systemDownregulation and upregulationImmunologyAntibodyBiologyImmunotherapyCancer researchTransplantationMicrobiologyMedicineBioinformaticsReceptorGeneticsInternal medicineGeneCancer Immunotherapy and BiomarkersGut microbiota and healthImmune Cell Function and Interaction