Targeting PD-L2–RGMb overcomes microbiome-related immunotherapy resistance
Joon Seok Park, Francesca S. Gazzaniga, Meng–Huang Wu, Amalia K. Luthens, Jacob E. Gillis, Wenfeng Zheng, Martin W. LaFleur, Sarah B. Johnson, Golnaz Morad, Elizabeth M. Park, Yifan Zhou, Stephanie S. Watowich, Jennifer A. Wargo, Gordon J. Freeman, Dennis L. Kasper, Arlene H. Sharpe
Topics & Concepts
BlockadeMicrobiomeImmune checkpointImmunityImmune systemDownregulation and upregulationImmunologyAntibodyBiologyImmunotherapyCancer researchTransplantationMicrobiologyMedicineBioinformaticsReceptorGeneticsInternal medicineGeneCancer Immunotherapy and BiomarkersGut microbiota and healthImmune Cell Function and Interaction