(±)-Hypandrone A, a pair of polycyclic polyprenylated acylphloroglucinol enantiomers with a caged 7/6/5/6/6 pentacyclic skeleton from <i>Hypericum androsaemum</i>
Jiangchun Wei, Pingping Fan, Yahui Huang, Hanxiao Zeng, Rui Jiang, Zhengzhi Wu, Yonghui Zhang, Zhengxi Hu
Abstract
(±)-Hypandrone A (1), a pair of highly modified PPAP enantiomers, with an unprecedented caged 2,8,17-trioxapentacyclo-[11.4.2.0 1,9 .0 4,9 .0 10,15 ]-nonadecane core, were isolated from the fruits of Hypericum androsaemum .
Topics & Concepts
ChemistryEnantiomerStereochemistryHypericumHypericinSkeleton (computer programming)AtropisomerTraditional medicinePharmacologyComputer scienceMedicineProgramming languageNatural Compound Pharmacology Studies