Iron-catalysed reductive coupling for the synthesis of polyfluorinated compounds
Yu‐Qiu Guan, Tian‐Zhang Wang, Jia-Fan Qiao, Zhangpei Chen, Zhushuang Bai, Yu‐Feng Liang
Abstract
-difluoroolefins. The cross-electrophile coupling displayed excellent functional group tolerance and broad substrate scope under mild reductive conditions, affording a large number of polyfluorinated compounds, which could be further transformed to other valuable molecules.
Topics & Concepts
ElectrophileChemistryRadicalSubstrate (aquarium)CatalysisFunctional groupTrifluoromethylReductive eliminationCombinatorial chemistryMetalCarbon fibersMoleculeOrganic chemistryAlkylMaterials sciencePolymerOceanographyComposite materialComposite numberGeologyFluorine in Organic ChemistryCatalytic C–H Functionalization MethodsRadical Photochemical Reactions