Increased nitrate intake from beetroot juice over 4 weeks affects nitrate metabolism, but not vascular function or blood pressure in older adults with hypertension
Rebeka Fejes, Martin Lutnik, Stefan Weisshaar, Nina Pilat, Karl‐Heinz Wagner, Hans‐Peter Stüger, Jonathan M. Peake, Richard Woodman, Kevin D. Croft, Catherine P. Bondonno, Jonathan M. Hodgson, Michael Wolzt, Oliver Neubauer
Abstract
> 0.05). These findings do not support the hypothesis that an increased intake of dietary nitrate exerts sustained beneficial effects on FBF or blood pressure in hypertensive older adults, providing important information on the efficacy of nitrate-based interventions for healthy vascular aging. This study was registered under ClinicialTrials.gov (NCT04584372).
Topics & Concepts
Crossover studyBlood pressureNitrateDietary NitratePlaceboMedicineInternal medicineMetabolismEssential hypertensionCardiologyEndocrinologyFood sciencePhysiologyChemistryNitriteBiologyEcologyAlternative medicinePathologySodium Intake and HealthNitric Oxide and Endothelin EffectsBlood Pressure and Hypertension Studies