Cofactor Specificity of Glucose-6-Phosphate Dehydrogenase Isozymes in Pseudomonas putida Reveals a General Principle Underlying Glycolytic Strategies in Bacteria
Daniel C. Volke, Karel Olavarría, Pablo I. Nikel
Abstract
specificity in bacterial species strongly correlates with their predominant metabolic lifestyle. Our findings support the notion that multiplication of genes encoding cofactor-dependent dehydrogenases is a general evolutionary strategy toward achieving redox balance according to the growth conditions.
Topics & Concepts
Pseudomonas putidaPentose phosphate pathwayCofactorDehydrogenaseIsozymeBiochemistryBiologyNAD+ kinaseBiovarGene isoformAlcohol dehydrogenaseEnzymeGeneGlycolysisGeneticsAmino Acid Enzymes and MetabolismEnzyme Structure and FunctionChemical Analysis and Environmental Impact