Trimethoprim-sulfamethoxazole resistance patterns among <i>Staphylococcus aureus</i> in the United States, 2012–2018
D. Cal Ham, Lucy Fike, Hannah Wolford, Lindsey Lastinger, Minn Soe, James Baggs, Maroya Spalding Walters
Abstract
Abstract We reviewed trimethoprim-sulfamethoxazole antibiotic susceptibility testing data among Staphylococcus aureus using 3 national inpatient databases. In all 3 databases, we observed an increases in the percentage of methicillin-resistant Staphylococcus aureus that were not susceptible to trimethoprim-sulfamethoxazole. Providers should select antibiotic regimens based on local resistance patterns and should report changes to the public health department.
Topics & Concepts
TrimethoprimStaphylococcus aureusSulfamethoxazoleMedicineMicrobiologyAntibioticsMethicillin-resistant Staphylococcus aureusAntibiotic resistanceBiologyBacteriaGeneticsAntimicrobial Resistance in StaphylococcusStreptococcal Infections and TreatmentsAntibiotic Resistance in Bacteria