Nucleophilic covalent ligand discovery for the cysteine redoxome
Ling Fu, Young-Eun Jung, Caiping Tian, Renan B. Ferreira, Ruifeng Cheng, Fuchu He, Jing Yang, Kate S. Carroll
Topics & Concepts
Sulfenic acidNucleophileChemistryCysteineLigand (biochemistry)BioconjugationSmall moleculeProteomeCombinatorial chemistryBiochemistryStereochemistryReceptorEnzymeCatalysisClick Chemistry and ApplicationsChemical Synthesis and AnalysisSynthesis and Catalytic Reactions