Calpain-2 regulates hypoxia/HIF-induced plasticity toward amoeboid cancer cell migration and metastasis
Veronika te Boekhorst, Liying Jiang, Marius Mählen, Maaike Meerlo, Gina Dunkel, Franziska C. Durst, Yanjun Yang, Herbert Levine, Boudewijn Burgering, Peter Friedl
Topics & Concepts
BiologyCalpainCell biologyCancer cellDownregulation and upregulationExtracellular matrixHypoxia (environmental)Cancer researchMetastasisIntegrinCell migrationCellCancerChemistryBiochemistryOxygenEnzymeGeneticsGeneOrganic chemistryCalpain Protease Function and RegulationAutophagy in Disease and TherapyCancer, Hypoxia, and Metabolism