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Exposure to the plasticizer, Di-(2-ethylhexyl) phthalate during juvenile period exacerbates autism-like behavior in adult BTBR T + tf/J mice due to DNA hypomethylation and enhanced inflammation in brain and systemic immune cells

Ahmed Nadeem, Naif O. Al‐Harbi, Sheikh F. Ahmad, Khalid Alhazzani, Sabry M. Attia, Sary Alsanea, Ali Alhoshani, Hafiz Majid Mahmood, Ali S. Alfardan, Saleh A. Bakheet

2021Progress in Neuro-Psychopharmacology and Biological Psychiatry43 citationsDOI

Topics & Concepts

PhthalateDNA methylationEpigeneticsInflammationAutismJuvenileEndocrinologyDNMT1Internal medicineMedicineBiologyChemistryGene expressionGeneGeneticsPsychiatryOrganic chemistryEffects and risks of endocrine disrupting chemicalsPluripotent Stem Cells Research
Exposure to the plasticizer, Di-(2-ethylhexyl) phthalate during juvenile period exacerbates autism-like behavior in adult BTBR T + tf/J mice due to DNA hypomethylation and enhanced inflammation in brain and systemic immune cells | Litcius