Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter
Yange Niu, Rui Liu, Chengcheng Guan, Yuan Zhang, Zhixing Chen, S. Hoerer, Herbert Nar, Lei Chen
Topics & Concepts
EmpagliflozinCotransporterChemistryTransporterPhlorizinGlucose transporterRenal glucose reabsorptionBiochemistryBiophysicsBiologySodiumType 2 diabetesDiabetes mellitusInsulinEndocrinologyGeneOrganic chemistryPancreatic function and diabetesDiabetes Treatment and ManagementMetabolism, Diabetes, and Cancer