Litcius/Paper detail

Synthesis of Sulfinamidines and Sulfinimidate Esters by Transfer of Nitrogen to Sulfenamides

Michael Andresini, Mauro Spennacchio, Giuseppe Romanazzi, Fulvio Ciriaco, Guy J. Clarkson, Leonardo Degennaro, Renzo Luisi

2020Organic Letters52 citationsDOIOpen Access PDF

Abstract

In this work we report a new synthetic tactic for the straightforward preparation of hardly accessible sulfinamidines and sulfinamide esters, by using a simple metal-free protocol. The process is robust and uses readily available sulfenamides as the S-donor and sulfonyloxycarbamates as the N-source. The scope and mechanism have also been investigated.

Topics & Concepts

ChemistryScope (computer science)Combinatorial chemistryNitrogenSimple (philosophy)Process (computing)Organic chemistryComputer scienceProgramming languagePhilosophyEpistemologySulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsCatalytic C–H Functionalization Methods